Multidisciplinary approach in the differential diagnosis of left ventricular hypertrophy: a case report

Abstract

Left ventricular (LV) hypertrophy implies structural cardiac changes and, as a consequence, an increase in myocardial mass. Currently, there are many causes of this condition as follows: hypertension, aortic stenosis, hypertrophic cardiomyopathy, exercise, storage diseases (AL, ATTR amyloidosis, Danon disease, Anderson-­Fabry disease, etc.), metabolic disorders. Despite the currently existing diagnostic algorithms for LV hypertrophy, establishing a correct diagnosis can take a long time, and controversial research results can lead to false conclusions. This article presents a case report of a patient with LV hypertrophy, an atypical clinical performance and ambiguous paraclinical data, which led to certain diagnostic difficulties.

Keywords

• left ventricular hypertrophy
• hypertrophic cardiomyopathy
• amyloidosis
• phenotype
• <i>myh7</i>
• cardiomyopathy
• magnetic resonance imaging
• case report