Effect of vitrectomy with intravitreal Conbercept injection for polypoidal choroidal vasculopathy associated with vitreous hemorrhage

Abstract

AIM: To investigate the clinical effect of vitrectomy combined with intravitreal injection of Conbercept for polypoidal choroidal vasculopathy(PCV)associated with vitreous hemorrhage. METHODS: The clinical data of 59 patients(59 eyes)underwent vitrectomy in a hospital from May 2013 to August 2016 were retrospectively analyzed. Among them, 21 cases treated with vitrectomy were set as the control group; 38 cases treated with vitrectomy combined with intravitreal injection of conbercept were set up as the observation group. The efficacy and safety of the two groups were observed. RESULTS: After the 12-month follow-up, the fundus examination of the observation group revealed that the deep, superficial retina hemorrhage and exudation of 38 patients were completely absorbed, and B-ultrasound showed that all patients with subretinal hemorrhage were also completely absorbed. However, B-ultrasound showed that subretinal hemorrhage and exudation still existed in 18 patients with varying degrees. The total BCVA changes before and after treatment in the two groups were statistically significant(PPPPχ2=35.680, PP>0.05). CONCLUSION: Vitrectomy combined with intravitreal injection of conbercept is an effective and safe way for PCV associated with vitreous hemorrhage.

Keywords

• polypoidal choroidal vasculopathy
• vitreous hemorrhage
• vitrectomy
• conbercept
• conbercept