Bioengineering (Jun 2022)

Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay

  • Han Zhuang,
  • Chun Xu,
  • Fang Gao,
  • Yiwei Li,
  • Chang Lei,
  • Chengzhong Yu

DOI
https://doi.org/10.3390/bioengineering9070266
Journal volume & issue
Vol. 9, no. 7
p. 266

Abstract

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Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica-nanomaterial-assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed.

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