EXPLORING NEW PROPERTIES KNOWN DRUGS. REPORT I. THEORETICAL EXPLANATION AS TO OBTAINING AND INVESTIGATION OF NEW DISAGGREGANTS BASED ON KNOWN DRUGS

Abstract

Search for new applications of known drugs is unique among methods of finding drugs. Significant sav-ings is the benefit of this approach. Known drugs are well studied, change their application does not require ex-tensive research accompanying the introduction of the pharmaceutical market of new substances. In this paper, an example of extending the scope of known drugs is shown by the example of promising research in a number of well-known disaggregants drugs using techniques of molecular modeling, quantum chemistry and multivariate statistical analysis.

Keywords

• molecular modeling
• new properties of known drugs
• the prognosis of biological activity
• disaggregants