The impact of concomitant syndrome of somatopsychic dysfunction on the quality of patients with chronic obstructive pulmonary disease life

Abstract

The aim – to estimate the quality of life (QOL) parameters in patients with chronic obstructive pulmonary disease (COPD), depending on the type and severity of concomitant clinically significant integrative syndrome of somatopsychic dysfunction (SPD). Materials and мethods. 306 COPD patients (224 (73.2 %) men and 82 (26.8 %) women, average age (65.3 ± 0.6) years) were examined by conventional methods in pulmonology practice. Among them clinical group A had 38 (12.4 %) patients, group B – 122 (39.9 %), group C – 28 (9.2 %), and a clinical group D – 118 (38.5 %) patients. The control group consisted of 100 healthy individuals and was representative to the main by age and gender. Psychic status of respondents was determined by the complex of standardized questionnaire method. QOL was assessed using the International Ukrainian version of the QOL questionnaire MOS SF-36. Statistical analysis of the data was made using statistical software package SPSS 20.0 for Windows. Results. It has been established that the prevalence of clinically significant integrative syndrome of SPD in COPD patients was 68 (22.2 %) patients and in the group of healthy individuals – 2 (2.0 %) persons. It has been found that patients with COPD had statistically significantly lower mean scores on all QOL parameters compared with healthy individuals (p < 0.001). The average values of all QOL parameters in COPD patients with clinically significant syndrome of SPD were statistically significantly lower than those in patients with insignificant disorders and compared with the average values in the entire cohort of COPD patients (p < 0.001). It has been established that in COPD patients with the same severity of the disease course the mean values of the QOL parameters were significantly decreased in the presence of a clinically significant SPD syndrome (p < 0.05). Conclusions. Thus, patients with COPD in the presence of clinically significant SPD syndrome are characterized by significantly lower average values of QOL parameters by indicators of physical, mental and social status, and this demonstrates the presence of maladaptation to the society in these patients.

Keywords

• chronic obstructive pulmonary disease
• quality of life
• syndrome of somatopsychic dysfunction