Arabian Journal of Chemistry (Nov 2014)

Neat synthesis and antioxidant activity of α-aminophosphonates

  • Guna Subba Reddy,
  • Kunda Uma Maheswara Rao,
  • Chereddy Syama Sundar,
  • Sarva Santhi Sudha,
  • Buchammagari Haritha,
  • Sirasanagandla Swapna,
  • Cirandur Suresh Reddy

DOI
https://doi.org/10.1016/j.arabjc.2013.01.004
Journal volume & issue
Vol. 7, no. 5
pp. 833 – 838

Abstract

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A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde and diethyl phosphite catalyzed by Amberlyst-15 has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions using microwave irradiation. The major advantages of the present method are inexpensive, ecofriendly and reusable catalyst and also studied their antioxidant activity of synthesized compounds.

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