Nature Communications (Sep 2021)

Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation

  • Bo Yang,
  • Shi-Jun Li,
  • Yongdong Wang,
  • Yu Lan,
  • Shifa Zhu

DOI
https://doi.org/10.1038/s41467-021-25594-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Although hydrogen atom transfer is widely observed in synthetic organic chemistry, intramolecular hydrogen atom transfer between atoms separated by fewer than four bonds is kinetically slow. Here the authors show a method to form indanones, with hydrogen atoms shuttled across short distances by water.