Kayexalate (Sodium Polystyrene Sulphonate) in Sorbitol Associated with Intestinal Necrosis in Uremic Patients

Abstract

BACKGROUND: Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency. Isolated case reports and one recent large series have documented intestinal necrosis following administration of kayexalate in sorbitol.