Food and Agricultural Immunology (Jan 2019)

Immune-enhancing effects of polysaccharides MLN-1 from by-product of Mai-luo-ning in vivo and in vitro

  • Linfeng Nie,
  • Qiuping Xiao,
  • Shuangshuang Liu,
  • Bo Li,
  • Jinao Duan,
  • Yanhong Fan,
  • Liwei Guo,
  • Chenghua He,
  • Huaxu Zhu

DOI
https://doi.org/10.1080/09540105.2019.1582612
Journal volume & issue
Vol. 30, no. 1
pp. 369 – 384

Abstract

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In this study, a typical Chinese medicine injection (Mai-luo-ning, MLN) was chosen to study the transformation possibility of its by-products (polysaccharides). What’s more, the basic properties of polysaccharides were also detected and its immunoprotect and anti-inflammatory activity were both proved in vivo and in vitro. The experiment determined that MLN-1 significantly increased the level of anti-inflammatory-related factors and the number of lymphocytes. Acute oral toxicity study established that MLN-1 has a non-toxic effect. The present work successfully showed that MLN-1 has the potential to be developed as a food additive.

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