Influence of Serum Ferritin and B12 Levels in the Functional Outcomes of Patients with Ruptured and Unruptured Intracranial Aneurysms

Abstract

Introduction Pathological processes in the arterial wall that result in vessel dilation are the cause of intracranial aneurysms (IAs), and the risk factors for their formation and progression are not well established. Ferritin is associated with inflammation and angiogenesis; it has protective antioxidative activity, and controls cell differentiation. Vitamin B12 is related to neurological and hematological disorders; it can be used as differential diagnosis tool, and acts in the control of homocysteinemia, a predictor of worse prognosis. The present article aims to assess the correlation between serum ferritin and B12 levels and the patient's functional outcome.

Keywords

• brain aneurysm
• ruptured intracranial aneurysm
• unruptured intracranial aneurysm
• subarachnoid hemorrhage
• serum ferritin
• serum B12
• aneurisma cerebral
• aneurisma intracraniano rompidoaneurisma intracraniano não rompidohemorragia subaracnóidea
• ferritina sérica
• B12 sérica