Acta Veterinaria (Dec 2019)

Chromosome Aberrations Produced by Mestranol in Human Lymphocyte Cultures

  • Teodorović Radislava,
  • Drašković Vladimir,
  • Đurić Spomenka,
  • Nenadović Kartarina,
  • Mirilović Milorad,
  • Janković Ljiljana

DOI
https://doi.org/10.2478/acve-2019-0036
Journal volume & issue
Vol. 69, no. 4
pp. 426 – 433

Abstract

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In this investigation, the genotoxic properties of mestranol were examined in vitro. Human lymphocyte cultures were exposed for 72 h to mestranol at concentrations of 7.5, 15 and 30 µg/g. The genotoxic effects of the chemosterilant were assessed by numerical and structural chromosome aberrations.

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