mBio (Feb 2021)
Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19
- Ryan M. Pace,
- Janet E. Williams,
- Kirsi M. Järvinen,
- Mandy B. Belfort,
- Christina D. W. Pace,
- Kimberly A. Lackey,
- Alexandra C. Gogel,
- Phuong Nguyen-Contant,
- Preshetha Kanagaiah,
- Theresa Fitzgerald,
- Rita Ferri,
- Bridget Young,
- Casey Rosen-Carole,
- Nichole Diaz,
- Courtney L. Meehan,
- Beatrice Caffé,
- Mark Y. Sangster,
- David Topham,
- Mark A. McGuire,
- Antti Seppo,
- Michelle K. McGuire
Affiliations
- Ryan M. Pace
- ORCiD
- Margaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA
- Janet E. Williams
- ORCiD
- Department of Animal, Veterinary, and Food Sciences, University of Idaho, Moscow, Idaho, USA
- Kirsi M. Järvinen
- Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
- Mandy B. Belfort
- Department of Pediatric Newborn Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
- Christina D. W. Pace
- Margaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA
- Kimberly A. Lackey
- Margaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA
- Alexandra C. Gogel
- Margaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA
- Phuong Nguyen-Contant
- David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
- Preshetha Kanagaiah
- David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
- Theresa Fitzgerald
- David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
- Rita Ferri
- Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
- Bridget Young
- Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
- Casey Rosen-Carole
- Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
- Nichole Diaz
- Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
- Courtney L. Meehan
- Department of Anthropology, Washington State University, Pullman, Washington, USA
- Beatrice Caffé
- Department of Anthropology, Washington State University, Pullman, Washington, USA
- Mark Y. Sangster
- ORCiD
- David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
- David Topham
- ORCiD
- David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
- Mark A. McGuire
- Department of Animal, Veterinary, and Food Sciences, University of Idaho, Moscow, Idaho, USA
- Antti Seppo
- Department of Pediatrics, Division of Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
- Michelle K. McGuire
- ORCiD
- Margaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA
- DOI
- https://doi.org/10.1128/mBio.03192-20
- Journal volume & issue
-
Vol. 12,
no. 1
Abstract
Results from prior studies assaying human milk for the presence of SARS-CoV-2, the causative virus of COVID-19, have suggested milk may act as a potential vehicle for mother-to-child transmission. Most previous studies are limited because they followed only a few participants, were cross-sectional, and/or failed to report how milk was collected and/or analyzed.
