Biosensors (Nov 2022)

Demonstrating a Filter-Free Wavelength Sensor with Double-Well Structure and Its Application

  • Yong-Joon Choi,
  • Kakeru Nakano,
  • Tomoya Ide,
  • Tsugumi Sakae,
  • Ryosuke Ichikawa,
  • Takeshi Hizawa,
  • Daisuke Akai,
  • Kazuhiro Takahashi,
  • Toshihiko Noda,
  • Kazuaki Sawada

DOI
https://doi.org/10.3390/bios12111033
Journal volume & issue
Vol. 12, no. 11
p. 1033

Abstract

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This study proposed a filter-free wavelength sensor with a double-well structure for detecting fluorescence without an optical filter. The impurity concentration was optimized and simulated to form a double-well-structured sensor, of which the result was consistent with the fabricated sensor. Furthermore, we proposed a novel wavelength detection method using the current ratio based on the silicon absorption coefficient. The results showed that the proposed method successfully detected single wavelengths in the 460–800 nm range. Additionally, we confirmed that quantification was possible using the current ratio of the sensor for a relatively wide band wavelength, such as fluorescence. Finally, the fluorescence that was emitted from the reagents ALEXA488, 594, and 680 was successfully identified and quantified. The proposed sensor can detect wavelengths without optical filters, which can be used in various applications in the biofield, such as POCT as a miniaturized wavelength detection sensor.

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