Journal of Translational Medicine (Dec 2022)

Long-term survivors demonstrate superior quality of life after haploidentical stem cell transplantation to matched sibling donor transplantation

  • Xiaoyu Zhang,
  • Jiao Wang,
  • Yuqiu Liu,
  • Jie Liu,
  • Bei Wang,
  • Qiuhui Zhang,
  • Wei Guan,
  • Huijuan Zhang,
  • Li Xu,
  • Guiying Liu,
  • Ping Zhang,
  • Yi He,
  • Sizhou Feng,
  • Mingzhe Han,
  • Changping Li,
  • Erlie Jiang,
  • Wenjun Xie

DOI
https://doi.org/10.1186/s12967-022-03803-y
Journal volume & issue
Vol. 20, no. 1
pp. 1 – 12

Abstract

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Key points Long-term survivors of HSCT recipients demonstrated longitudinal recovery in QoL which can be quantified with both SF-36 and FACT-BMT forms Recipients of HID-HSCT reported higher performance of QoL in both mental and physical dimensions. History of acute GVHD or CMV reactivation significantly was associated with inferior QoL. The SF-36 and FACT-BMT forms demonstrated different performance in the quantification of QoL recovery and combination of both may improve QoL evaluation system

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