Nature Communications (Jun 2022)
Short- and long-read metagenomics expand individualized structural variations in gut microbiomes
- Liang Chen,
- Na Zhao,
- Jiabao Cao,
- Xiaolin Liu,
- Jiayue Xu,
- Yue Ma,
- Ying Yu,
- Xuan Zhang,
- Wenhui Zhang,
- Xiangyu Guan,
- Xiaotong Yu,
- Zhipeng Liu,
- Yanqun Fan,
- Yang Wang,
- Fan Liang,
- Depeng Wang,
- Linhua Zhao,
- Moshi Song,
- Jun Wang
Affiliations
- Liang Chen
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Na Zhao
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Jiabao Cao
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Xiaolin Liu
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Jiayue Xu
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Yue Ma
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Ying Yu
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Xuan Zhang
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Wenhui Zhang
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Xiangyu Guan
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- Xiaotong Yu
- Guang’anmen Hospital, China Academy of Chinese Medical Sciences
- Zhipeng Liu
- Biotree-Shanghai
- Yanqun Fan
- Biotree-Shanghai
- Yang Wang
- GrandOmics Biosciences
- Fan Liang
- GrandOmics Biosciences
- Depeng Wang
- GrandOmics Biosciences
- Linhua Zhao
- Guang’anmen Hospital, China Academy of Chinese Medical Sciences
- Moshi Song
- University of Chinese Academy of Sciences
- Jun Wang
- CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
- DOI
- https://doi.org/10.1038/s41467-022-30857-9
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
Here, Wang and colleagues combine short and long sequencing reads to characterize structural variations, prophage and CRISPR spacer elements in human gut microbiomes, and reveal functional differences at a finer level of bacterial strains.
