口腔疾病防治 (Oct 2022)

Research progress on basic fibroblast growth factor in promoting periodontal tissue regeneration

  • ZHANG Peipei,
  • LI Hongyan,
  • TIAN Yue,
  • CHEN Huishan,
  • LIN Hongbing,
  • SHEN Yuqin

DOI
https://doi.org/10.12016/j.issn.2096-1456.2022.10.012
Journal volume & issue
Vol. 30, no. 10
pp. 757 – 760

Abstract

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Basic fibroblast growth factor (bFGF) exhibits superior biological functions by improving periodontal inflammation, promoting the migration and proliferation of periodontal-related stem cells, promoting the formation of blood vessels and periodontal ligament-like tissue, and regulating the formation of bone/cementum. It plays an important role in tooth development, repair and regeneration. bFGF can be combined with seed cells and scaffold materials for periodontal tissue regeneration, which has been verified in a number of experimental studies. However, the application of bFGF alone as a drug in clinical treatment requires further research.

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