Pharmacodynamics of frigid zone plant Taxus cuspidata S. et Z. against skin melanin deposition, oxidation, inflammation and allergy

Shi Yang; Liu Ling; Sun Heyang; Chen Chen; Feng Jing; Chen Yongchao; Lin Yuan; Kopylov Philipp; Wang Qi; Zhang Yong

doi:10.2478/fzm-2023-0007

Frigid Zone Medicine (Jan 2023)

Pharmacodynamics of frigid zone plant Taxus cuspidata S. et Z. against skin melanin deposition, oxidation, inflammation and allergy

Shi Yang,
Liu Ling,
Sun Heyang,
Chen Chen,
Feng Jing,
Chen Yongchao,
Lin Yuan,
Kopylov Philipp,
Wang Qi,
Zhang Yong

Affiliations

Shi Yang: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Liu Ling: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Sun Heyang: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Chen Chen: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Feng Jing: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Chen Yongchao: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Lin Yuan: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China
Kopylov Philipp: Department of Preventive and Emergency Cardiology, Sechenov First Moscow State Medical University, Moscow119991, Russia
Wang Qi: Department of Medicinal chemistry and natural medicinal chemistry, College of Pharmacy, Harbin Medical University, Harbin150081, China
Zhang Yong: Department of Pharmacology (the State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin150081, China

DOI: https://doi.org/10.2478/fzm-2023-0007
Journal volume & issue: Vol. 3, no. 1
pp. 42 – 52

Abstract

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Taxus cuspidata S. et Z. is a precious species of frigid zone plant belonging to the Taxaceae family, which possesses anticancer, anti-inflammatory, hypoglycemic, and antibacterial pharmacological properties. While taxane extracted from Taxus chinensis has been reported to elicit antioxidant activities, whether Taxus cuspidata S. et Z. has skin-protective actions against injuries remained unknown. This study aims to explore the pharmacological effects of three Taxus extracts on skin melanin deposition, oxidation, inflammation, and allergy so as to provide new ideas for the prevention and treatment of various diseases related to skin damage.

Published in Frigid Zone Medicine

ISSN: 2719-8073 (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Medicine: Internal medicine: Special situations and conditions
Website: https://www.degruyter.com/journal/key/fzm/html

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