Association between occlusal support and cognitive impairment in older Chinese adults: a community-based study

Dongxin Da; Dongxin Da; Suyu Ge; Suyu Ge; Hao Zhang; Hao Zhang; Xiaoli Zeng; Xiaoli Zeng; Yiwei Jiang; Yiwei Jiang; Jin Yu; Jin Yu; Huning Wang; Huning Wang; Wanqing Wu; Wanqing Wu; Wanqing Wu; Zhenxu Xiao; Zhenxu Xiao; Zhenxu Xiao; Xiaoniu Liang; Xiaoniu Liang; Xiaoniu Liang; Qianhua Zhao; Qianhua Zhao; Qianhua Zhao; Ding Ding; Ding Ding; Ding Ding; Ying Zhang; Ying Zhang

doi:10.3389/fnagi.2023.1146335

Frontiers in Aging Neuroscience (Apr 2023)

Association between occlusal support and cognitive impairment in older Chinese adults: a community-based study

Dongxin Da,
Dongxin Da,
Suyu Ge,
Suyu Ge,
Hao Zhang,
Hao Zhang,
Xiaoli Zeng,
Xiaoli Zeng,
Yiwei Jiang,
Yiwei Jiang,
Jin Yu,
Jin Yu,
Huning Wang,
Huning Wang,
Wanqing Wu,
Wanqing Wu,
Wanqing Wu,
Zhenxu Xiao,
Zhenxu Xiao,
Zhenxu Xiao,
Xiaoniu Liang,
Xiaoniu Liang,
Xiaoniu Liang,
Qianhua Zhao,
Qianhua Zhao,
Qianhua Zhao,
Ding Ding,
Ding Ding,
Ding Ding,
Ying Zhang,
Ying Zhang

Affiliations

Dongxin Da: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Dongxin Da: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Suyu Ge: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Suyu Ge: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Hao Zhang: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Hao Zhang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Xiaoli Zeng: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Xiaoli Zeng: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Yiwei Jiang: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Yiwei Jiang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Jin Yu: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Jin Yu: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Huning Wang: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Huning Wang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Wanqing Wu: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Wanqing Wu: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Wanqing Wu: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Zhenxu Xiao: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Zhenxu Xiao: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Zhenxu Xiao: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Xiaoniu Liang: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Xiaoniu Liang: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Xiaoniu Liang: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Qianhua Zhao: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Qianhua Zhao: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Qianhua Zhao: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Ding Ding: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Ding Ding: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Ding Ding: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Ying Zhang: Department of Preventive Dentistry, Shanghai Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, China
Ying Zhang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China

DOI: https://doi.org/10.3389/fnagi.2023.1146335
Journal volume & issue: Vol. 15

Abstract

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IntroductionThe loss of occlusal support due to tooth loss is associated with systemic diseases. However, there was little about the association between occlusal support and cognitive impairment. The cross-sectional study aimed to investigate their association.MethodsCognitive function was assessed and diagnosed in 1,225 community-dwelling adults aged 60 years or older in Jing’an District, Shanghai. Participants were diagnosed with mild cognitive impairment (MCI) by Peterson’s criteria, or dementia, according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. We determined the number of functional occlusal supporting areas according to Eichner classifications. We used multivariate logistic regression models to analyze the relationship between occlusal support and cognitive impairment and mediation effect models to analyze the mediation effect of age.ResultsSix hundred sixty participants were diagnosed with cognitive impairment, averaging 79.92 years old. After adjusting age, sex, education level, cigarette smoking, alcohol drinking, cardiovascular disease, and diabetes, individuals with poor occlusal support had an OR of 3.674 (95%CI 1.141–11.829) for cognitive impairment compared to those with good occlusal support. Age mediated 66.53% of the association between the number of functional occlusal supporting areas and cognitive impairment.DiscussionIn this study, cognitive impairment was significantly associated with the number of missing teeth, functional occlusal areas, and Eichner classifications with older community residents. Occlusal support should be a significant concern for people with cognitive impairment.

Published in Frontiers in Aging Neuroscience

ISSN: 1663-4365 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: https://www.frontiersin.org/journals/aging-neuroscience

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