Frontiers in Digital Health (Jun 2022)

Leveraging Mobile-Based Sensors for Clinical Research to Obtain Activity and Health Measures for Disease Monitoring, Prevention, and Treatment

  • Hari G. Dandapani,
  • Natalie M. Davoodi,
  • Natalie M. Davoodi,
  • Lucie C. Joerg,
  • Melinda M. Li,
  • Daniel H. Strauss,
  • Daniel H. Strauss,
  • Kelly Fan,
  • Talie Massachi,
  • Elizabeth M. Goldberg,
  • Elizabeth M. Goldberg

DOI
https://doi.org/10.3389/fdgth.2022.893070
Journal volume & issue
Vol. 4

Abstract

Read online

Clinical researchers are using mobile-based sensors to obtain detailed and objective measures of the activity and health of research participants, but many investigators lack expertise in integrating wearables and sensor technologies effectively into their studies. Here, we describe the steps taken to design a study using sensors for disease monitoring in older adults and explore the benefits and drawbacks of our approach. In this study, the Geriatric Acute and Post-acute Fall Prevention Intervention (GAPcare), we created an iOS app to collect data from the Apple Watch's gyroscope, accelerometer, and other sensors; results of cognitive and fitness tests; and participant-entered survey data. We created the study app using ResearchKit, an open-source framework developed by Apple for medical research that includes neuropsychological tests (e.g., of executive function and memory), gait speed, balance, and other health assessments. Data is transmitted via an Application Programming Interface (API) from the app to REDCap for researchers to monitor and analyze in real-time. Employing the lessons learned from GAPcare could help researchers create study-tailored research apps and access timely information about their research participants from wearables and smartphone devices for disease prevention, monitoring, and treatment.

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