Magnetic covalent organic frameworks combined with HPLC for determination of alkylphenols
Ting Cheng,
Yan-Xin Chen,
Zi-Yu Li,
Jia-Hui Zhu,
Jie Zhao,
Yu-Shen Liu,
Lu-Liang Wang
Affiliations
Ting Cheng
School of Food Engineering, Ludong University, Yantai, 264025, China
Yan-Xin Chen
School of Food Engineering, Ludong University, Yantai, 264025, China
Zi-Yu Li
School of Food Engineering, Ludong University, Yantai, 264025, China
Jia-Hui Zhu
School of Food Engineering, Ludong University, Yantai, 264025, China
Jie Zhao
School of Food Engineering, Ludong University, Yantai, 264025, China
Yu-Shen Liu
School of Food Engineering, Ludong University, Yantai, 264025, China; Institute of Bionanotechnology, Yantai Engineering Research Center of Green Food Processing and Quality Control, Yantai Key Laboratory of Nanoscience and Technology for Prepared Food, Yantai, Shandong 264025, PR China
Lu-Liang Wang
School of Food Engineering, Ludong University, Yantai, 264025, China; Institute of Bionanotechnology, Yantai Engineering Research Center of Green Food Processing and Quality Control, Yantai Key Laboratory of Nanoscience and Technology for Prepared Food, Yantai, Shandong 264025, PR China; Corresponding author.
Alkylphenols are widely applied in the field of industry and agriculture, but their endocrine disrupting properties harm to human health. Moreover, alkylphenols often exhibit the low content in complex samples. Thus, we proposed magnetic covalent organic framework composites (Fe3O4@TatTpa) for efficient magnetic solid phase extraction (MSPE) of alkylphenols via hydrogen bonding, π-π and hydrophobic interactions. In combination with HPLC detection, good linearity (0.006–10 µg mL−1) with R2 (≥0.997) and low limit of detections (1.8–6 × 10−3 µg mL−1) were realized for alkylphenols. The proposed method was successfully employed to determine alkylphenols in soft drink, black oolong tea, and watermelon samples with satisfactory recoveries (86.1–118.5 %) and relative standard deviations (6.3–14.8 %).
