Erythrocytes' rheological properties in patients with arterial hypertension and dyslipidemia against simvastatin therapy

Abstract

The purpose - to investigate the influence of an inhibitor hydroxymetilglutaril A-reductase - Simvastatin on rheological properties of erythrocytes in patients with arterial hypertension and dyslipidemia. Administration of Simvastatin for 1 year normalizes the lipid profile and the levels of lipid peroxidation of plasma and erythrocytes. As a result of 52 weeks' of treatment with Simvastatin in patients with hypertension and dyslipidemia, cytoarchitectonics of erythrocytes and their aggregation activity were improved, reaching a level of standards.

Keywords

• эритроциты
• реология крови
• артериальная гипертония
• дислипидемия и симвастатин