Communications Biology (Feb 2023)
Interpersonal variability of the human gut virome confounds disease signal detection in IBD
- Stephen R. Stockdale,
- Andrey N. Shkoporov,
- Ekaterina V. Khokhlova,
- Karen M. Daly,
- Siobhan A. McDonnell,
- Orla O’ Regan,
- James A. Nolan,
- Thomas D. S. Sutton,
- Adam G. Clooney,
- Feargal J. Ryan,
- Donal Sheehan,
- Aonghus Lavelle,
- Lorraine A. Draper,
- Fergus Shanahan,
- R. Paul Ross,
- Colin Hill
Affiliations
- Stephen R. Stockdale
- APC Microbiome Ireland, University College Cork, Co
- Andrey N. Shkoporov
- APC Microbiome Ireland, University College Cork, Co
- Ekaterina V. Khokhlova
- APC Microbiome Ireland, University College Cork, Co
- Karen M. Daly
- APC Microbiome Ireland, University College Cork, Co
- Siobhan A. McDonnell
- APC Microbiome Ireland, University College Cork, Co
- Orla O’ Regan
- APC Microbiome Ireland, University College Cork, Co
- James A. Nolan
- APC Microbiome Ireland, University College Cork, Co
- Thomas D. S. Sutton
- APC Microbiome Ireland, University College Cork, Co
- Adam G. Clooney
- APC Microbiome Ireland, University College Cork, Co
- Feargal J. Ryan
- APC Microbiome Ireland, University College Cork, Co
- Donal Sheehan
- Department of Medicine, University College Cork, Co
- Aonghus Lavelle
- APC Microbiome Ireland, University College Cork, Co
- Lorraine A. Draper
- APC Microbiome Ireland, University College Cork, Co
- Fergus Shanahan
- APC Microbiome Ireland, University College Cork, Co
- R. Paul Ross
- APC Microbiome Ireland, University College Cork, Co
- Colin Hill
- APC Microbiome Ireland, University College Cork, Co
- DOI
- https://doi.org/10.1038/s42003-023-04592-w
- Journal volume & issue
-
Vol. 6,
no. 1
pp. 1 – 10
Abstract
A longitudinal analysis of unamplified fecal virome of healthy controls and IBD patients reveals interpersonal variability is a factor that limits our ability to identify associations between the virome composition and IBD.
