Haematologica (Aug 2017)
Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia
- Dimitrios Papaioannou,
- Deedra Nicolet,
- Stefano Volinia,
- Krzysztof Mrózek,
- Pearlly Yan,
- Ralf Bundschuh,
- Andrew J. Carroll,
- Jessica Kohlschmidt,
- William Blum,
- Bayard L. Powell,
- Geoffrey L. Uy,
- Jonathan E. Kolitz,
- Eunice S. Wang,
- Ann-Kathrin Eisfeld,
- Shelley J. Orwick,
- David M. Lucas,
- Michael A. Caligiuri,
- Richard M. Stone,
- John C. Byrd,
- Ramiro Garzon,
- Clara D. Bloomfield
Affiliations
- Dimitrios Papaioannou
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Deedra Nicolet
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA;The Alliance for Clinical Trials in Oncology Statistics and Data Center, Mayo Clinic, Rochester, MN, USA
- Stefano Volinia
- Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Italy
- Krzysztof Mrózek
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Pearlly Yan
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Ralf Bundschuh
- Department of Physics, Department of Chemistry & Biochemistry, Division of Hematology, Department of Internal Medicine, Center for RNA Biology, The Ohio State University, Columbus, OH, USA
- Andrew J. Carroll
- Department of Genetics, University of Alabama at Birmingham, AL, USA
- Jessica Kohlschmidt
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA;The Alliance for Clinical Trials in Oncology Statistics and Data Center, Mayo Clinic, Rochester, MN, USA
- William Blum
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Bayard L. Powell
- The Comprehensive Cancer Center of Wake Forest University, Winston-Salem, NC, USA
- Geoffrey L. Uy
- Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA
- Jonathan E. Kolitz
- Hofstra North Shore-Long Island Jewish School of Medicine, Lake Success, NY, USA
- Eunice S. Wang
- Roswell Park Cancer Institute, Buffalo, NY, USA
- Ann-Kathrin Eisfeld
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Shelley J. Orwick
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- David M. Lucas
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Michael A. Caligiuri
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Richard M. Stone
- Dana-Farber Cancer Institute, Harvard University, Boston, MA, USA
- John C. Byrd
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Ramiro Garzon
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- Clara D. Bloomfield
- The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA
- DOI
- https://doi.org/10.3324/haematol.2017.166215
- Journal volume & issue
-
Vol. 102,
no. 8
Abstract
Long non-coding ribonucleic acids (RNAs) are a novel class of RNA molecules, which are increasingly recognized as important molecular players in solid and hematologic malignancies. Herein we investigated whether long non-coding RNA expression is associated with clinical and molecular features, as well as outcome of younger adults (aged
