Hypertensive Urgency after Administration of a Single Low Dose of Mirtazapine- A Case Report

Jiana Shi; Xiaojun Wang; Yin Ying; Lin Xu; Danyan Zhu

Iranian Journal of Public Health (Feb 2015)

Hypertensive Urgency after Administration of a Single Low Dose of Mirtazapine- A Case Report

Jiana Shi,
Xiaojun Wang,
Yin Ying,
Lin Xu,
Danyan Zhu

Affiliations

Jiana Shi: Dept. of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, China AND Dept. of Pharmacology, Toxicology and Biochemical Pharmaceutics, Zhejiang University, Hangzhou, China.
Xiaojun Wang: Dept. of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Yin Ying: Dept. of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Lin Xu: Dept. of Cardiovascular Medicine, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Danyan Zhu: Dept. of Pharmacology, Toxicology and Biochemical Pharmaceutics, Zhejiang University, Hangzhou, China.

Journal volume & issue: Vol. 44, no. 2

Abstract

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Mirtazapine is a new antidepressant that can increase noradrenergic and serotonergic neurotransmission. It is also a postsynaptic antagonist of 5-HT2 and 5-HT3. In addition, it has only a weak affinity for 5-HT1 receptors and has very weak muscarinic anticholinergic and histamine (H1) antagonist properties. We report a case of hypertensive urgency that ensued after a patient took a single low dose of mirtazapine.

Published in Iranian Journal of Public Health

ISSN: 2251-6085 (Print); 2251-6093 (Online)
Publisher: Tehran University of Medical Sciences
Country of publisher: Iran, Islamic Republic of
LCC subjects: Medicine: Public aspects of medicine
Website: http://ijph.tums.ac.ir/index.php/IJPH/index

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Abstract

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