To further evaluate the clinical usefulness of serum neopterin measurement as a parameter monitoring disease activity in children with ulcerative colitis, serum neopterin concentrations were evaluated using immunoenzyme assay (ELISA) in 48 patients suffering from ulcerative colitis with different disease activity. Statistically significant differences in serum neopterin concentration depending on disease activity (according to Truelove-Witts score) as well as statistically significant positive correlation between these variables were observed. We conclude that serum neopterin measurement can be clinically valuable as the parameter monitoring disease activity in children with ulcerative colitis.
