Diffusion-mediated HEI10 coarsening can explain meiotic crossover positioning in Arabidopsis

Chris Morgan; John A. Fozard; Matthew Hartley; Ian R. Henderson; Kirsten Bomblies; Martin Howard

doi:10.1038/s41467-021-24827-w

Nature Communications (Aug 2021)

Diffusion-mediated HEI10 coarsening can explain meiotic crossover positioning in Arabidopsis

Chris Morgan,
John A. Fozard,
Matthew Hartley,
Ian R. Henderson,
Kirsten Bomblies,
Martin Howard

Affiliations

Chris Morgan: John Innes Centre, Norwich Research Park
John A. Fozard: John Innes Centre, Norwich Research Park
Matthew Hartley: John Innes Centre, Norwich Research Park
Ian R. Henderson: Department of Plant Sciences, University of Cambridge
Kirsten Bomblies: Institute of Molecular Plant Biology, Department of Biology, Swiss Federal Institute of Technology (ETH) Zürich
Martin Howard: John Innes Centre, Norwich Research Park

DOI: https://doi.org/10.1038/s41467-021-24827-w
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 11

Abstract

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Crossover numbers and positions are tightly controlled but the mechanism involved is still obscure. Here, the authors, using quantitative super-resolution cytogenetics and mathematical modelling, show that diffusion mediated coarsening of HEI10, an E3-ligase domain containing protein, may explain meiotic crossover positioning in Arabidopsis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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