Atomic and Specificity Details of Mucin 1 O‑Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling

• Helena Coelho,
• Matilde de las Rivas,
• Ana S. Grosso,
• Ana Diniz,
• Cátia O. Soares,
• Rodrigo A. Francisco,
• Jorge S. Dias,
• Ismael Compañon,
• Lingbo Sun,
• Yoshiki Narimatsu,
• Sergey Y. Vakhrushev,
• Henrik Clausen,
• Eurico J. Cabrita,
• Jesús Jiménez-Barbero,
• Francisco Corzana,
• Ramon Hurtado-Guerrero,
• Filipa Marcelo

Affiliations

Helena Coelho

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Matilde de las Rivas

Institute for Biocomputation and Physics of Complex Systems (BIFI), Laboratorio de Microscopias Avanzadas (LMA), University of Zaragoza, Zaragoza, Spain

Ana S. Grosso

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Ana Diniz

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Cátia O. Soares

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Rodrigo A. Francisco

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Jorge S. Dias

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Ismael Compañon

Departamento de Química, Centro de Investigación en Síntesis Química, Universidad de La Rioja, Logroño, Spain

Lingbo Sun

Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark

Yoshiki Narimatsu

Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark

Sergey Y. Vakhrushev

Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark

Henrik Clausen

Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark

Eurico J. Cabrita

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal

Jesús Jiménez-Barbero

CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Spain

Francisco Corzana

Departamento de Química, Centro de Investigación en Síntesis Química, Universidad de La Rioja, Logroño, Spain

Ramon Hurtado-Guerrero

Institute for Biocomputation and Physics of Complex Systems (BIFI), Laboratorio de Microscopias Avanzadas (LMA), University of Zaragoza, Zaragoza, Spain

Filipa Marcelo

Associate Laboratory i4HBInstitute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal