中西医结合护理 (Feb 2025)
Current status and risk factors of cognitive frailty in elderly patients with ischemic stroke (老年缺血性脑卒中患者认知衰弱现状及危险因素分析)
Abstract
Objective To investigate the current status and risk factors of cognitive frailty in elderly patients with ischemic stroke. Methods A convenience sample of 182 elderly ischemic stroke patients attending a tertiary-level hospital from January 2022 to December 2022 was selected as study subjects. The FRAIL scale and the Brief Mental State Examination Scale were used to screen for cognitive decline, and the general and clinical data of the patients were collected to analyze the risk factors for cognitive decline by univariate analysis and binary logistic regression. Results The prevalence of cognitive frailty in elderly ischemic stroke patients was 48. 90%, and logistic regression analysis showed that age, comorbid diabetes mellitus, NHISS scores, low physical activity, high variety of medications, malnutrition, and depression were the risk factors for cognitive weakness in elderly ischemic stroke patients (P＜0. 05). Conclusion Elderly ischemic stroke patients have a high prevalence of cognitive frailty, and the clinical work focuses on patients with advanced age, combined diabetes, and low physical activity level, which should be subject to early screening and nutritional interventions, and at the same time should be reasonably medicated, pay attention to neurological function recovery, and intervene in depression at an early stage, so as to reverse or delay the progression of cognitive weakness in elderly ischemic stroke patients. (目的 探讨老年缺血性脑卒中患者认知衰弱现状及危险因素。方法 采取便利抽样选取医院2022年1月—12月就诊的182例老年缺血性脑卒中患者作为研究对象。采用FRAIL量表、简易精神状态检查量表筛查认知衰弱, 收集患者的一般资料和临床资料, 通过单因素分析和二元Logistic回归分析认知衰弱的危险因素。结果 老年缺血性脑卒中患者认知衰弱的患病率为48. 90%。Logistic回归分析显示年龄、合并糖尿病、NHISS评分、低体力活动、服药种类多、营养不良、抑郁是老年缺血性脑卒中患者认知衰弱的危险因素(P＜0. 05)。结论 老年缺血性脑卒中患者具有较高的认知衰弱患病率, 临床工作中重点关注高龄、合并糖尿病、低体力活动水平患者, 应对其进行早期筛查和营养干预, 同时要合理用药, 关注神经功能恢复情况, 早期干预抑郁情绪, 逆转或延缓老年缺血性脑卒中患者认知衰弱的进展。)
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