Cardiology Journal (Jun 2025)
Short- and long-term outcomes of Impella-protected, high-risk, elective PCI in patients with multivessel coronary disease and low ejection fraction — Polish Impella Registry
- Wojciech J. Skorupski,
- Arkadiusz Pietrasik,
- Aleksandra Gąsecka,
- Jerzy Sacha,
- Tomasz Pawłowski,
- Gabriel Bielawski,
- Wojciech Balak,
- Adam Sukiennik,
- Paulina Burzyńska,
- Adam Witkowski,
- Mateusz Warniełło,
- Łukasz Rzeszutko,
- Stanisław Bartuś,
- Artur Pawlik,
- Mateusz Kaczyński,
- Robert Gil,
- Wiktor Kuliczkowski,
- Krzysztof Reczuch,
- Marcin Protasiewicz,
- Jacek Legutko,
- Paweł Kleczyński,
- Piotr Wańczura,
- Sebastian Gurba,
- Anna Kochanowska,
- Michał Łomiak,
- Maciej Krajsman,
- Włodzimierz Skorupski,
- Maciej Zarębiński,
- Piotr Pawluczuk,
- Szymon Włodarczak,
- Adrian Włodarczak,
- Krzysztof Ściborski,
- Artur Telichowski,
- Mieszko Pluciński,
- Jarosław Hiczkiewicz,
- Karolina Konsek,
- Michał Hawranek,
- Mariusz Gąsior,
- Jan Peruga,
- Marcin Fiutowski,
- Robert Romanek,
- Piotr Kasprzyk,
- Dariusz Ciećwierz,
- Andrzej Ochała,
- Wojciech Wojakowski,
- Janusz Kochman,
- Maciej Lesiak,
- Marek Grygier
Affiliations
- Wojciech J. Skorupski
- 1st Department of Cardiology, Poznan University of Medical Sciences, Poland
- Arkadiusz Pietrasik
- Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
- Aleksandra Gąsecka
- Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
- Jerzy Sacha
- Department of Cardiology, University Hospital in Opole, Opole, Poland
- Tomasz Pawłowski
- National Medical Institute of the Internal Affairs ad Administration Ministry, Warsaw, Poland
- Gabriel Bielawski
- 2nd Department of Cardiology, Jan Biziel University Hospital No. 2, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
- Wojciech Balak
- 2nd Department of Cardiology, Jan Biziel University Hospital No. 2, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
- Adam Sukiennik
- Department of Cardiology and Internal Diseases, University Hospital No. 1, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
- Paulina Burzyńska
- Department of Cardiology and Internal Diseases, University Hospital No. 1, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
- Adam Witkowski
- Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland
- Mateusz Warniełło
- Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland
- Łukasz Rzeszutko
- Department of Cardiology, University Hospital, Krakow, Poland
- Stanisław Bartuś
- Department of Cardiology, University Hospital, Krakow, Poland
- Artur Pawlik
- Department of Cardiology, University Hospital, Krakow, Poland
- Mateusz Kaczyński
- National Medical Institute of the Internal Affairs ad Administration Ministry, Warsaw, Poland
- Robert Gil
- National Medical Institute of the Internal Affairs ad Administration Ministry, Warsaw, Poland
- Wiktor Kuliczkowski
- Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
- Krzysztof Reczuch
- Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
- Marcin Protasiewicz
- Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
- Jacek Legutko
- Jagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, Krakow, Poland
- Paweł Kleczyński
- Jagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, Krakow, Poland
- Piotr Wańczura
- College of Medical Sciences, University of Rzeszow, Rzeszow, Poland
- Sebastian Gurba
- College of Medical Sciences, University of Rzeszow, Rzeszow, Poland
- Anna Kochanowska
- Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
- Michał Łomiak
- Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
- Maciej Krajsman
- Department of Medical Informatics and Telemedicine, Medical University of Warsaw, Warsaw, Poland
- Włodzimierz Skorupski
- 1st Department of Cardiology, Poznan University of Medical Sciences, Poland
- Maciej Zarębiński
- Independent Public Specialist Western Hospital John Paul II in Grodzisk Mazowiecki, Poland
- Piotr Pawluczuk
- Independent Public Specialist Western Hospital John Paul II in Grodzisk Mazowiecki, Poland
- Szymon Włodarczak
- Department of Cardiology, The Copper Health Centre (MCZ), Lubin, Poland
- Adrian Włodarczak
- Department of Cardiology, The Copper Health Centre (MCZ), Lubin, Poland
- Krzysztof Ściborski
- Center for Heart Diseases, Military Hospital in Wroclaw, Wroclaw, Poland
- Artur Telichowski
- Center for Heart Diseases, Military Hospital in Wroclaw, Wroclaw, Poland
- Mieszko Pluciński
- University of Zielona Gora, Collegium Medicum, Department of Interventional Cardiology and Cardiac Surgery, Zielona Gora, Poland
- Jarosław Hiczkiewicz
- University of Zielona Gora, Collegium Medicum, Department of Interventional Cardiology and Cardiac Surgery, Zielona Gora, Poland
- Karolina Konsek
- 3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland
- Michał Hawranek
- 3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland
- Mariusz Gąsior
- 3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland
- Jan Peruga
- 1st Department of Cardiology, Bieganski Hospital, Medical University, Lodz, Poland
- Marcin Fiutowski
- 1st Department of Cardiology, Bieganski Hospital, Medical University, Lodz, Poland
- Robert Romanek
- Department of Cardiology and Cardiac Surgery, 10th Military Hospital and Polyclinic, Bydgoszcz, Poland
- Piotr Kasprzyk
- 1st Department of Cardiology, Medical University of Gdansk, Gdansk, Poland
- Dariusz Ciećwierz
- 1st Department of Cardiology, Medical University of Gdansk, Gdansk, Poland
- Andrzej Ochała
- Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
- Wojciech Wojakowski
- Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
- Janusz Kochman
- Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
- Maciej Lesiak
- 1st Department of Cardiology, Poznan University of Medical Sciences, Poland
- Marek Grygier
- 1st Department of Cardiology, Poznan University of Medical Sciences, Poland
- DOI
- https://doi.org/10.5603/cj.103336
- Journal volume & issue
-
Vol. 32,
no. 3
Abstract
BACKGROUND: The Impella percutaneous mechanical circulatory support device provides improved support in treating patients with high-risk percutaneous coronary interventions (HR-PCI) or in cardiogenic shock. IMPELLA-PL is a multicenter registry developed to share clinical data and experiences using Impella technology in Poland. The retrospective analysis conducted in this study aims to fill the knowledge gap of Impella performance in patients with multivessel coronary artery disease (CAD) and depressed left ventricular ejection fraction (EF) (≤30%) treated with HR-PCI. METHODS: Retrospective data were analyzed from patients presenting with multivessel coronary disease and low EF treated with Impella CP collected from 20 Polish interventional cardiology centers registered with IMPELLA-PL to assess the safety and efficacy in short- and long-term clinical outcomes. RESULTS: A total of 115 patients with low EF received Impella CP support during HR-PCI. The success rate of Impella supported HR-PCI was high (99.1%) with an average hospital stay of 15.6 ± 10.7 days. The right femoral artery was the most common access (55.7%) followed by the left femoral artery (37.4%). The in-hospital mortality rate was 6.1%, and the all-cause mortality rate at one year was 13.9%. CONCLUSIONS: High-risk PCI with Impella CP periprocedural support was safe and effective in patients with low EF (≤30%). The all-cause mortality rate (6.1% and 13.9%, respectively, for in-hospital and at 12-months) was comparable with other Impella registries.
Keywords
