Computational Psychiatry (Jan 2022)

Feasibility Analysis of Phenotype Quantification from Unstructured Clinical Interactions

  • Daniel S. Barron,
  • Stephen Heisig,
  • Carla Agurto,
  • Raquel Norel,
  • Brittany Quagan,
  • Albert Powers,
  • Michael L. Birnbaum,
  • Todd Constable,
  • Guillermo Cecchi,
  • John H. Krystal

DOI
https://doi.org/10.5334/cpsy.78
Journal volume & issue
Vol. 6, no. 1

Abstract

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We conducted a feasibility analysis to determine the quality of data that could be collected ambiently during routine clinical conversations. We used inexpensive, consumer-grade hardware to record unstructured dialogue and open-source software tools to quantify and model face, voice (acoustic and language) and movement features. We used an external validation set to perform proof-of-concept predictive analyses and show that clinically relevant measures can be produced without a restrictive protocol.

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