Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus

Roger Castells-Graells; Jonas R. S. Ribeiro; Tatiana Domitrovic; Emma L. Hesketh; Charlotte A. Scarff; John E. Johnson; Neil A. Ranson; David M. Lawson; George P. Lomonossoff

doi:10.1038/s42003-021-02134-w

Communications Biology (May 2021)

Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus

Roger Castells-Graells,
Jonas R. S. Ribeiro,
Tatiana Domitrovic,
Emma L. Hesketh,
Charlotte A. Scarff,
John E. Johnson,
Neil A. Ranson,
David M. Lawson,
George P. Lomonossoff

Affiliations

Roger Castells-Graells: Department of Biological Chemistry, John Innes Centre
Jonas R. S. Ribeiro: Virology Department, Instituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro
Tatiana Domitrovic: Virology Department, Instituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro
Emma L. Hesketh: Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds
Charlotte A. Scarff: Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds
John E. Johnson: Department of Integrative Structural and Computational Biology, The Scripps Research Institute
Neil A. Ranson: Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds
David M. Lawson: Department of Biological Chemistry, John Innes Centre
George P. Lomonossoff: Department of Biological Chemistry, John Innes Centre

DOI: https://doi.org/10.1038/s42003-021-02134-w
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 12

Abstract

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Castells-Graells et al. demonstrate the maturation of insect virus Nudaurelia capensis omega virus (NωV) capsids in a plant model. This shows plants are a useful tool in the study of eukaryotic viruses across Kingdoms, and they identify new features in the maturation of the NωV capsid.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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