Intravitreal Injection of Bevacizumab to Treat a Macular Edema Caused by Leber’s Miliary Aneurysm

Abstract

Purpose: Leber’s miliary aneurysm is a variant of Coats’ disease and similar to type 1 idiopathic macular telangiectasia. A recent report showed that an intravitreal injection of bevacizumab (IVB) was effective in an adult patient with type 1 idiopathic macular telangiectasia. We describe our experience with an adult patient with a macular edema caused by Leber’s miliary aneurysm, which had not been resolved by prior retinal laser photocoagulation, who underwent IVB. Methods: We investigated the ocular characteristics of the patient before and after a single administration of IVB. Results: The macular edema had partially improved 1 month after IVB, but then it worsened. We performed laser photocoagulation to treat the aneurysms near the fovea. The macular edema improved, but there was no improvement in visual acuity. Conclusion: In this patient, the effect of IVB was limited.

Keywords

• Bevacizumab
• Intravitreal injection
• Leber’s miliary aneurysm
• Macular edema