A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice
Jean-Charles Preiser,
Yaseen M. Arabi,
Mette M. Berger,
Michael Casaer,
Stephen McClave,
Juan C. Montejo-González,
Sandra Peake,
Annika Reintam Blaser,
Greet Van den Berghe,
Arthur van Zanten,
Jan Wernerman,
Paul Wischmeyer
Affiliations
Jean-Charles Preiser
Erasme University Hospital, Université Libre de Bruxelles
Yaseen M. Arabi
Intensive Care Department, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs
Mette M. Berger
Adult Intensive Care, Lausanne University Hospital, CHUV
Michael Casaer
Clinical Department and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, Katholieke Universiteit Leuven
Stephen McClave
Department of Medicine, University of Louisville School of Medicine
Juan C. Montejo-González
Intensive Care Medicine, Hospital Universitario
Sandra Peake
Department of Intensive Care Medicine, The Queen Elizabeth Hospital
Annika Reintam Blaser
Department of Intensive Care Medicine, Lucerne Cantonal Hospital
Greet Van den Berghe
Clinical Department and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, Katholieke Universiteit Leuven
Arthur van Zanten
Ede and Division of Human Nutrition and Health, Gelderse Vallei Hospital, Wageningen University and Research
Jan Wernerman
Division of Anaesthesiology and Intensive Care Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet
Paul Wischmeyer
Department of Anesthesiology and Surgery, Duke University School of Medicine
Abstract The preferential use of the oral/enteral route in critically ill patients over gut rest is uniformly recommended and applied. This article provides practical guidance on enteral nutrition in compliance with recent American and European guidelines. Low-dose enteral nutrition can be safely started within 48 h after admission, even during treatment with small or moderate doses of vasopressor agents. A percutaneous access should be used when enteral nutrition is anticipated for ≥ 4 weeks. Energy delivery should not be calculated to match energy expenditure before day 4–7, and the use of energy-dense formulas can be restricted to cases of inability to tolerate full-volume isocaloric enteral nutrition or to patients who require fluid restriction. Low-dose protein (max 0.8 g/kg/day) can be provided during the early phase of critical illness, while a protein target of > 1.2 g/kg/day could be considered during the rehabilitation phase. The occurrence of refeeding syndrome should be assessed by daily measurement of plasma phosphate, and a phosphate drop of 30% should be managed by reduction of enteral feeding rate and high-dose thiamine. Vomiting and increased gastric residual volume may indicate gastric intolerance, while sudden abdominal pain, distension, gastrointestinal paralysis, or rising abdominal pressure may indicate lower gastrointestinal intolerance.