PLoS ONE (Jan 2013)

In vitro electrochemical corrosion and cell viability studies on nickel-free stainless steel orthopedic implants.

  • Erfan Salahinejad,
  • Mohammad Jafar Hadianfard,
  • Digby Donald Macdonald,
  • Samin Sharifi-Asl,
  • Masoud Mozafari,
  • Kenneth J Walker,
  • Armin Tahmasbi Rad,
  • Sundararajan V Madihally,
  • Lobat Tayebi

DOI
https://doi.org/10.1371/journal.pone.0061633
Journal volume & issue
Vol. 8, no. 4
p. e61633

Abstract

Read online

The corrosion and cell viability behaviors of nanostructured, nickel-free stainless steel implants were studied and compared with AISI 316L. The electrochemical studies were conducted by potentiodynamic polarization and electrochemical impedance spectroscopic measurements in a simulated body fluid. Cytocompatibility was also evaluated by the adhesion behavior of adult human stem cells on the surface of the samples. According to the results, the electrochemical behavior is affected by a compromise among the specimen's structural characteristics, comprising composition, density, and grain size. The cell viability is interpreted by considering the results of the electrochemical impedance spectroscopic experiments.