Claisen, Cope and Related Rearrangements in the Synthesis of Flavour and Fragrance Compounds

Abstract

A review of the use of the Claisen, Cope and related [3,3]-sigmatropic rearrangements, sequential ("tandem") sigmatropic rearrangements and the "ene" reaction in the syntheses of flavour and fragrance compounds is presented.

Keywords

• Claisen rearrangements
• Cope rearrangements
• Caroll rearrangements
• tandem sigmatropic rearrangements
• "ene" reactions
• flavour and fragrance compounds