Communications Biology (Feb 2022)
The Antarctic Weddell seal genome reveals evidence of selection on cardiovascular phenotype and lipid handling
- Hyun Ji Noh,
- Jason Turner-Maier,
- S. Anne Schulberg,
- Michael L. Fitzgerald,
- Jeremy Johnson,
- Kaitlin N. Allen,
- Luis A. Hückstädt,
- Annabelle J. Batten,
- Jessica Alfoldi,
- Daniel P. Costa,
- Elinor K. Karlsson,
- Warren M. Zapol,
- Emmanuel S. Buys,
- Kerstin Lindblad-Toh,
- Allyson G. Hindle
Affiliations
- Hyun Ji Noh
- Broad Institute of MIT and Harvard
- Jason Turner-Maier
- Broad Institute of MIT and Harvard
- S. Anne Schulberg
- Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School
- Michael L. Fitzgerald
- Lipid Metabolism Unit, Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School
- Jeremy Johnson
- Broad Institute of MIT and Harvard
- Kaitlin N. Allen
- Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School
- Luis A. Hückstädt
- Institute of Marine Sciences, Department of Ecology and Evolutionary Biology, University of California Santa Cruz
- Annabelle J. Batten
- Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School
- Jessica Alfoldi
- Broad Institute of MIT and Harvard
- Daniel P. Costa
- Institute of Marine Sciences, Department of Ecology and Evolutionary Biology, University of California Santa Cruz
- Elinor K. Karlsson
- Broad Institute of MIT and Harvard
- Warren M. Zapol
- Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School
- Emmanuel S. Buys
- Broad Institute of MIT and Harvard
- Kerstin Lindblad-Toh
- Broad Institute of MIT and Harvard
- Allyson G. Hindle
- Broad Institute of MIT and Harvard
- DOI
- https://doi.org/10.1038/s42003-022-03089-2
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 12
Abstract
The Antarctic Weddell inhabits one of the most extreme environments on Earth. Comparative genomics with close relatives reveals the specific genetic adaptations for cardiovascular and fat metabolism that enable it to thrive.
