A hybrid approach for diagnosing diabetic retinopathy from fundus image exploiting deep features

Abstract

One of the major causes of blindness in human beings is the diabetic retinopathy (DR). To prevent blindness, early detection of DR is therefore necessary. In this paper, a hybrid model is proposed for diagnosing DR from fundus images. A combination of morphological image processing and Inception v3 deep learning techniques are exploited to detect DR as well as to classify healthy, mild non-proliferative DR (NPDR), moderate NPDR, severe NPDR, and proliferative DR (PDR). The proposed algorithm was carried out in several steps such as segmentation of blood vessels, localization and removal of optic disc, and macula, abnormal features detection (microaneurysms, hemorrhages, and neovascularization), and classification. Microaneurysms and hemorrhages that appear in the retina are the early signs of DR. In this work, we have detected microaneurysms and hemorrhages by applying dynamic contrast limited adaptive histogram equalization and threshold value on overlapping patched images. An overall accuracy of 96.83% is obtained to classify DR into five different stages. The better performance demonstrates the effectiveness and novelty of the proposed work as compared to the recent reported work.

Keywords

• Abnormal lesions detection
• Deep learning
• Diabetic retinopathy
• Fundus image
• Image processing
• Inception v3