Correction to: DNMT3A reads and connects histone H3K36me2 to DNA methylation

Wenqi Xu; Jiahui Li; Bowen Rong; Bin Zhao; Mei Wang; Ruofei Dai; Qilong Chen; Hang Liu; Zhongkai Gu; Shuxian Liu; Rui Guo; Hongjie Shen; Feizhen Wu; Fei Lan

doi:10.1007/s13238-019-00678-6

Protein & Cell (Dec 2019)

Correction to: DNMT3A reads and connects histone H3K36me2 to DNA methylation

Wenqi Xu,
Jiahui Li,
Bowen Rong,
Bin Zhao,
Mei Wang,
Ruofei Dai,
Qilong Chen,
Hang Liu,
Zhongkai Gu,
Shuxian Liu,
Rui Guo,
Hongjie Shen,
Feizhen Wu,
Fei Lan

Affiliations

Wenqi Xu: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Jiahui Li: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Bowen Rong: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Bin Zhao: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Mei Wang: Department of Geriatrics, Shanghai General Hospital
Ruofei Dai: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Qilong Chen: Research Center for Chinese Traditional Medicine Complexity System, Shanghai University of Chinese Traditional Medicine
Hang Liu: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Zhongkai Gu: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Shuxian Liu: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Rui Guo: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Hongjie Shen: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Feizhen Wu: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University
Fei Lan: Key Laboratory of Birth Defects, Children’s Hospital, Fudan University, and Key Laboratory of Epigenetics, Institutes of Biomedical Sciences, Fudan University

DOI: https://doi.org/10.1007/s13238-019-00678-6
Journal volume & issue: Vol. 11, no. 3
pp. 230 – 230

Abstract

Read online

The author would like to add the below information in this correction. A similar study from Chao Lu group was published online on 5 September 2019 in Nature, entitled “The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape” (Weinberg et al., 2019). Although both the studies reported the preferential recognition of H3K36me2 by DNMT3A PWWP, ours in addition uncovered a stimulation function by such interaction on the activity of DNMT3A. On the disease connections, we used a NSD2 gain-of-function model which led to the discovery of potential therapeutic implication of DNA inhibitors in the related cancers, while the other study only used NSD1 and DNMT3A loss-of-function models.

Published in Protein & Cell

ISSN: 1674-800X (Print); 1674-8018 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Cytology; Science: Physiology: Animal biochemistry
Website: https://academic.oup.com/proteincell

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