Nature Communications (Mar 2022)

Waning of SARS-CoV-2 booster viral-load reduction effectiveness

  • Matan Levine-Tiefenbrun,
  • Idan Yelin,
  • Hillel Alapi,
  • Esma Herzel,
  • Jacob Kuint,
  • Gabriel Chodick,
  • Sivan Gazit,
  • Tal Patalon,
  • Roy Kishony

DOI
https://doi.org/10.1038/s41467-022-28936-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 4

Abstract

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The BNT162b2 COVID-19 vaccine has been shown to reduce viral load of breakthrough infections (BTIs). Here, analyzing viral loads of BTIs post third vaccine shot, Levine-Tiefenbrun et al. show waning of the booster’s effectiveness in reducing infectiousness within months, mirroring the rate and magnitude of decline observed post the second shot.