Application of New Supercritical Extraction Technology in Extraction and Separation of Effective Components of Traditional Chinese Medicine

Abstract

Supercritical CO2 extraction technology uses supercritical CO2 fluid as extractant to extract and separate effective components from plants from liquid or solid. At present, CO2 is widely used in supercritical fluid, with a critical temperature of 31.265 °C and a critical pressure of 7.18 MPa. The critical conditions are easy to reach. In supercritical state, the density of CO2 fluid is very sensitive to the changes of temperature and pressure, The widely used separation technologies can be divided into two types: membrane separation and traditional separation. The traditional separation methods can be divided into steam distillation, sublimation, cold soaking, precipitation, percolation, decocting method and Soxhlet extraction, etc. These separation methods have certain limitations. In this paper, SFE technology is combined with modern analytical techniques, such as gas chromatography, high performance liquid chromatography, thin layer chromatography, gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, etc., so that the component analysis can be carried out more efficiently and quickly. Because of the above advantages, SFE is especially beneficial to the extraction of effective components in traditional Chinese medicine and its preparations.

Keywords

• new technology of supercritical extraction
• active ingredients of traditional chinese medicine
• extraction and separation