Dataset of mitochondrial genome variants in oncocytic tumors
Lihua Lyu,
Qiufeng Wang,
Shujie Song,
Huaibin Zhou,
Ming Li,
Chen Zhou,
Zhiying Jiang,
Liyan Li,
Jianxin Lyu,
Guorong Chen,
Yidong Bai
Affiliations
Lihua Lyu
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Qiufeng Wang
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Shujie Song
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Huaibin Zhou
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Ming Li
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Chen Zhou
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Zhiying Jiang
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Liyan Li
Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
Jianxin Lyu
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
Guorong Chen
Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
Yidong Bai
School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA; Corresponding author at: School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
This dataset presents the mitochondrial genome variants associated with oncocytic tumors. These data were obtained by Sanger sequencing of the whole mitochondrial genomes of oncocytic tumors and the adjacent normal tissues from 32 patients. The mtDNA variants are identified after compared with the revised Cambridge sequence, excluding those defining haplogroups of our patients. The pathogenic prediction for the novel missense variants found in this study was performed with the Mitimpact 2 program.
