Synthesis of α-amino amides via α-amino imidoylbenzotriazoles

Katritzky Alan R.; Mohapatra Prabhu P.; Singh Shailendra; Clemens Nicole; Kirichenko Kostyantyn

doi:10.2298/JSC0503319K

Journal of the Serbian Chemical Society (Jan 2005)

Synthesis of α-amino amides via α-amino imidoylbenzotriazoles

Katritzky Alan R.,
Mohapatra Prabhu P.,
Singh Shailendra,
Clemens Nicole,
Kirichenko Kostyantyn

Affiliations

Katritzky Alan R.: University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA
Mohapatra Prabhu P.: University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA
Singh Shailendra: University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA
Clemens Nicole: University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA
Kirichenko Kostyantyn: University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA

DOI: https://doi.org/10.2298/JSC0503319K
Journal volume & issue: Vol. 70, no. 3
pp. 319 – 327

Abstract

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Reactions of isonitriles 11a-c with N-(α-aminoalkyl)benzotriazoles 10a-k afford N-(α-aminoimidoyl)benzotriazoles 12a-q which on hydrolysis by dilute hydrochloric acid gave α-amino amides 14a-j.

Published in Journal of the Serbian Chemical Society

ISSN: 0352-5139 (Print); 1820-7421 (Online)
Publisher: Serbian Chemical Society
Country of publisher: Serbia
LCC subjects: Science: Chemistry
Website: http://www.shd-pub.org.rs/index.php/JSCS

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