Crosstalk between heredity and environment in myopia: An overviewKey Messages
Jiawen Hao,
Zhaohui Yang,
Ruixue Zhang,
Zhongyu Ma,
Jinpeng Liu,
Hongsheng Bi,
Dadong Guo
Affiliations
Jiawen Hao
Shandong University of Traditional Chinese Medicine, Jinan, 250002, China
Zhaohui Yang
Shandong University of Traditional Chinese Medicine, Jinan, 250002, China
Ruixue Zhang
Shandong University of Traditional Chinese Medicine, Jinan, 250002, China
Zhongyu Ma
Shandong University of Traditional Chinese Medicine, Jinan, 250002, China
Jinpeng Liu
Shandong University of Traditional Chinese Medicine, Jinan, 250002, China
Hongsheng Bi
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250002, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Jinan, 250002, China; Shandong Academy of Eye Disease Prevention and Therapy, Jinan, 250002, China; Shandong Provincial Clinical Research Center of Ophthalmology and Children Visual Impairment Prevention and Control, Jinan, 250002, China; Shandong Engineering Technology Research Center of Visual Intelligence, Jinan, 250002, China; Shandong Academy of Health and Myopia Prevention and Control of Children and Adolescents, Jinan, 250002, China; Medical College of Optometry and Ophthalmology, Shandong University of Traditional Chinese Medicine, Jinan, 250002, China; Corresponding author. Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, No. 48#, Yingxiongshan Road, Jinan, Shandong, 250002, China.
Dadong Guo
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250002, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Jinan, 250002, China; Shandong Academy of Eye Disease Prevention and Therapy, Jinan, 250002, China; Shandong Provincial Clinical Research Center of Ophthalmology and Children Visual Impairment Prevention and Control, Jinan, 250002, China; Shandong Engineering Technology Research Center of Visual Intelligence, Jinan, 250002, China; Shandong Academy of Health and Myopia Prevention and Control of Children and Adolescents, Jinan, 250002, China; Medical College of Optometry and Ophthalmology, Shandong University of Traditional Chinese Medicine, Jinan, 250002, China; Corresponding author. Shandong Academy of Eye Disease Prevention and Therapy, No. 48#, Yingxiongshan Road, Jinan, 250002, China.
In recent years, the prevalence of myopia has gradually increased, and it has become a significant global public health problem in the 21st century, posing a serious challenge to human eye health. Currently, it is confirmed that the development of myopia is attributed to the combined action of genes and environmental factors. Thus, elucidating the risk factors and pathogenesis of myopia is of great significance for the prevention and control of myopia. To elucidate the impact of gene-environment interaction on myopia, we used the Pubmed database to search for literature related to myopia. Search terms are as follows: myopia, genes, environmental factors, gene-environment interaction, and treatment. This paper reviews the effects of gene and environmental interaction on myopia.
