TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters

Binlong Sun; Xiaoyu Tian; Sen Yang; Yingying Wang; Yingying Shao; Xinhao Fu; Wenyuan Wang; Minting Tu; Yang Chen; Junhui Wu; Changyuan Wu; Chengxia Tan

doi:10.3390/ijms232213704

International Journal of Molecular Sciences (Nov 2022)

TBPEH-TBPB Initiate the Radical Addition of Benzaldehyde and Allyl Esters

Binlong Sun,
Xiaoyu Tian,
Sen Yang,
Yingying Wang,
Yingying Shao,
Xinhao Fu,
Wenyuan Wang,
Minting Tu,
Yang Chen,
Junhui Wu,
Changyuan Wu,
Chengxia Tan

Affiliations

Binlong Sun: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Xiaoyu Tian: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Sen Yang: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Yingying Wang: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Yingying Shao: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Xinhao Fu: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Wenyuan Wang: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Minting Tu: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Yang Chen: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Junhui Wu: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Changyuan Wu: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Chengxia Tan: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China

DOI: https://doi.org/10.3390/ijms232213704
Journal volume & issue: Vol. 23, no. 22
p. 13704

Abstract

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Tert-butylperoxy-2-ethylhexanoate (TBPEH) and tert-butyl peroxybenzoate (TBPB) promote the radical acylation of allyl ester with benzaldehyde to synthesize new carbonyl-containing compounds under solvent-free and metal-free conditions. This reaction is compatible with electron-donating and halogen groups and has excellent atom utilization and chemical selectivity. Furthermore, the synthetic compounds can further apply to the preparation of lactone, piperidine, tetrazole and oxazole.

Published in International Journal of Molecular Sciences

ISSN: 1661-6596 (Print); 1422-0067 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General); Science: Chemistry
Website: http://www.mdpi.com/journal/ijms

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