中西医结合护理 (Jul 2023)
Effect of Traditional Chinese Medicine collapse stains combined with ultrasound drug penetration therapy in the treatment of diabetic peripheral neuropathy in the elderly (中药塌渍治疗联合超声药物导入治疗老年糖尿病周围神经病变的效果观察)
Abstract
Objective To investigate the effect of Traditional Chinese Medicine (TCM) collapse stains combined with ultrasound drug penetration therapy in the treatment of diabetic peripheral neuropathy (DPN)in the elderly. Methods Totally 90 elderly patients with DPN were randomly divided into observation group (n=45) and control group (n=45) . All patients received oral administration of Mecobalamin tablets combined with ultrasound drug penetration therapy, and patients in the observation group were given Traditional Chinese Medicine collapse stains additionally. Both two groups received 14-day course of treatment. The total clinical effective rate, clinical symptom score, sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV) of median nerve and common peroneal nerve were observed and compared between two groups. Results The total effective rate of the control group was 77. 78%(35/45), and total clinical effective rate of the treatment group was 93. 33%(42/45), with a significant difference (P＜0. 05). The clinical symptom scores of the two groups were significantly decreased after intervention(P＜0. 01), and clinical symptom score of the observation group was lower than that of the control group(P＜0. 01). MCV and SCV values of median nerve and common peroneal nerve in the two groups were significantly increased after intervention (P＜0. 01), and MNCV and SNCV values in the observation group were higher than those in the control group (P＜0. 01). Conclusion TCM collapse stains combined with ultrasound drug penetration therapy can effectively relieve the clinical symptoms of elderly patients with DPN, improve the motor and sensory conduction function of peripheral nerves, and the combined treatment can effectively improve the clinical treatment effect. (目的 探讨中药塌渍联合超声药物导入治疗老年糖尿病患者周围神经病变(DPN)的效果。方法 采用随机数字表将90例老年糖尿病周围神经病变(DPN)患者随机分为观察组(n=45)和对照组(n=45)。对照组给予甲钴胺片口服联合超声药物导入治疗, 观察组在对照组的基础上联合中药塌渍进行治疗, 两组均以14d为1个疗程, 连续治疗2个疗程。评估和对比两组临床总有效率、临床症状积分、治疗前后正中神经和腓总神经的感觉神经传导速度(SNCV)与运动神经传导速度(MNCV)的差异。结果 观察组总有效率为93. 33%(42/45), 高于对照组的77. 78%(35/45), 差异有统计学意义(P＜0. 05)。治疗后, 两组临床症状总积分较治疗前下降(P＜0. 01), 且观察组临床症状总积分下降幅度较对照组明显, 差异有统计学意义(P＜0. 01)。治疗后, 两组患者MNCV和SNCV数值较治疗前升高(P＜0. 01); 与对照组相比, 观察组MNCV和SNCV数值升高幅度优于对照组, 差异有统计学意义(P＜0. 01)。结论 中药塌渍治疗联合超声药物导入疗法可以有效缓解老年DPN患者临床症状和体征, 改善周围神经的运动和感觉传导功能, 联合治疗能有效提高临床治疗效果。)
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