Stroke and Vascular Neurology (Jun 2020)
Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of cerebral venous sinus thrombosis
- ,
- Jian Zhang,
- Liping Liu,
- Anding Xu,
- Xin Wang,
- Yongjun Wang,
- Kangning Chen,
- Dapeng Mo,
- Yilong Wang,
- Zhongrong Miao,
- Yuming Xu,
- Benyan Luo,
- Bin Peng,
- Yong Huo,
- Xingquan Zhao,
- Jizong Zhao,
- Wei Wang,
- Shuo Wang,
- Chen Wang,
- Linong Ji,
- Shizheng Wu,
- Yi Yang,
- Bo Wang,
- Junbo Ge,
- Xunming Ji,
- Tong Zhang,
- Bo Hu,
- Tielin Li,
- Ning Wang,
- Peng Xie,
- Yun Xu,
- Jinsheng Zeng,
- Chaodong Zhang,
- Zhuo Zhang,
- Gang Zhao,
- Yuhua Fan,
- Jian Yu,
- Hongbing Chen,
- Jiangang Duan,
- Wenhao Zhu,
- Fubing Ouyang,
- Yicong Chen,
- Linfang Lan,
- Li Guo; Li He,
- Xiaoyuan Niu,
- Dingfeng Su,
- Beisha Tang
Affiliations
- Jian Zhang
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Liping Liu
- 1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Anding Xu
- 5 Department of Neurology, The First Affiliated Hospital, Jinan University Guangzhou, Guangzhou, Guangdong, China
- Xin Wang
- Yongjun Wang
- 1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Kangning Chen
- Dapeng Mo
- 3 Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Yilong Wang
- 1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Zhongrong Miao
- 6 Neurointervention center, Beijing Tiantan Hospital, Beijing, China
- Yuming Xu
- 4 Zhengzhou University First Affiliated Hospital, Zhengzhou, China
- Benyan Luo
- Bin Peng
- Yong Huo
- Xingquan Zhao
- 1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Jizong Zhao
- Wei Wang
- Shuo Wang
- Chen Wang
- Linong Ji
- Shizheng Wu
- Yi Yang
- Bo Wang
- 3 Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Junbo Ge
- Xunming Ji
- Tong Zhang
- Bo Hu
- 1 Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
- Tielin Li
- Ning Wang
- Peng Xie
- Yun Xu
- Jinsheng Zeng
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Chaodong Zhang
- Zhuo Zhang
- Gang Zhao
- Yuhua Fan
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Jian Yu
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Hongbing Chen
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Jiangang Duan
- 2 Department of Neurology and Department of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, China
- Wenhao Zhu
- 4 Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Fubing Ouyang
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Yicong Chen
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Linfang Lan
- 1 Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China
- Li Guo; Li He
- Xiaoyuan Niu
- Dingfeng Su
- Beisha Tang
- DOI
- https://doi.org/10.1136/svn-2020-000358
- Journal volume & issue
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Vol. 5,
no. 2
Abstract
Aim Cerebral venous sinus thrombosis (CVST) is a less common cerebrovascular disease that predominantly affects young patients. The incidence of CVST is 2–5/10 000 000/year, accounting for 0.5%–1% of all stroke. To reduce mortality and morbidity associated with CVST, Chinese Stroke Association commissioned the authors to write the current guideline on the management of CVST.Methods PubMed (MEDLINE), CNKI and Wanfang database were searched for studies related to CVST from 1 January 1990 to 31 July 2019. Data were synthesised by evidence tables. Each recommendation was fully discussed by the writing group members and reviewed by Chinese Stroke Association Stroke Fellow Committees. Levels of evidence grading algorithm of Chinese Stroke Association was used to grade each recommendation.Results This guideline mainly focuses on the diagnostic evaluation, therapeutic strategies and secondary prevention of CVST. CT/CTV and MRI/MRV are recommended in the initial imaging evaluation of patients with suspected CVST. Anticoagulation therapy with low-molecular weight heparin should be initiated in patients with CVST immediately. After the acute stage, warfarin is recommended for 3–6 months to prevent the recurrence of CVST and other venous thromboembolic events.Conclusions The guideline summarises the current evidence regarding the management of CVST, and provides references for diagnosis, treatment and secondary prevention of CVST in China.
