Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure

Yuki Miyamoto; Tomohiro Torii; Masashi Inoue; Takako Morimoto; Masahiro Yamamoto; Junji Yamauchi

Data in Brief (Jun 2018)

Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure

Yuki Miyamoto,
Tomohiro Torii,
Masashi Inoue,
Takako Morimoto,
Masahiro Yamamoto,
Junji Yamauchi

Affiliations

Yuki Miyamoto: Laboratory of Molecular Neuroscience and Neurology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0355, Japan; Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan
Tomohiro Torii: Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
Masashi Inoue: Laboratory of Molecular Neuroscience and Neurology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0355, Japan
Takako Morimoto: Laboratory of Molecular Neuroscience and Neurology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0355, Japan
Masahiro Yamamoto: Tsumura Research Laboratories, Tsumura & Co., Inashiki, Ibaraki 200-1192, Japan
Junji Yamauchi: Laboratory of Molecular Neuroscience and Neurology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0355, Japan; Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan; Corresponding author at: Laboratory of Molecular Neuroscience and Neurology,School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. Fax: +81 42 676 8841.

Journal volume & issue: Vol. 18
pp. 803 – 807

Abstract

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Schwann cells in the peripheral nervous system wrap around large diameter axons to form the myelin sheath, that contains one axon. Schwann cells also wrap around small diameter axons to form the Remak bundle, that contains many axons. Neuregulin-1 (NRG1) type III binds Schwann cell plasma membrane ErbB2/3 receptor to regulate morphological changes of Schwann cells. Herein we provide the data on the effect of NRG1 type III knockout (Miyamoto et al., 2017) [1] on the Remak bundle structure. Since complete knockout mice of NRG1type III are embryonically lethal, we have usedNRG1type III (+/−) mice's sciatic nerves in these experiments. Keywords: Neuregulin-1, Knockout, Remak bundle, Sciatic nerve

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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