Clinical features of eyelid demodex infection in patients with meibomian gland dysfunction

Abstract

AIM:To analyze the clinical features of ectopic demodex infection in patients with meibomian gland dysfunction. METHODS: A retrospective study. Totally 220 patients(440 eyes)with meibomian gland dysfunction were selected from November 2016 to June 2018. They were divided into uninfected group and infected group according to the concurrence of eyelash demodex infection. 110 patients(220 eyes)in each group. The ocular function indexes of the two groups were tested and compared, and the clinical characteristics of eyelash demodex infection were evaluated.RESULTS: The incidence of itching, foreign body sensation, eye pain, dryness and astringency in the infected group was significantly higher than that in the non-infected group(PP>0.05); the average tear film rupture time and basic tear secretion in the two groups were significantly lower than that in the normal level, and the infected group was significantly lower than that in the non-infected group(PPCONCLUSION: Patients with tarsal gland dysfunction are more likely to suffer from itching, dryness, eye pain and other symptoms after eyelash demodex infection, which increases the damage of corneal and conjunctival epithelium. It is of great significance to pay attention to demodex infection examination for patients with tarsal gland dysfunction.

Keywords

• meibomian gland dysfunction
• demodex infection
• tear secretion
• meibomian gland secretion