Plants (Apr 2022)

<i>Bergenia pacumbis</i> (Buch.-Ham. ex D.Don) C.Y.Wu & J.T.Pan: A Comprehensive Review on Traditional Uses, Phytochemistry and Pharmacology

  • Apurba Gohain,
  • Ajay Sharma,
  • Hirok Jyoti Gogoi,
  • Raymond Cooper,
  • Ramandeep Kaur,
  • Gulzar Ahmad Nayik,
  • Ayaz Mukarram Shaikh,
  • Béla Kovács,
  • Franklin Ore Areche,
  • Mohammad Javed Ansari,
  • Nadiyah M. Alabdallah,
  • Ammar AL-Farga

DOI
https://doi.org/10.3390/plants11091129
Journal volume & issue
Vol. 11, no. 9
p. 1129

Abstract

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The influence of medicinal plants on humanity spans time immemorial. These plants are also used at present with local and tribal peoples for the cures of various illnesses. Nature has produced an immense number of medicinal plants, which directly or indirectly help to treat various ailments and have numerous applications in the fields of pharmaceuticals, agriculture, food flavors and preservatives, aromas, and cosmetics. Bergenia pacumbis (Buch.-Ham. ex D.Don) C.Y.Wu & J.T.Pan (synonym: Bergenia ligulate Engl.), is an important medicinal plant belonging to the Saxifragaceae family, and not to be confused with Bergenia ciliata (Haw.) Sternb., and is popularly known as Pashanbheda (meaning to dissolve the kidney stone). This plant is a rich source of secondary metabolites (SMs) such as coumarins, flavonoids, benzenoids, lactones, tannins, phenols, and sterols, which make this plant a highly valued medicinal herb with a broad spectrum of pharmacological activities such as anti-urolithic, antioxidant, anti-viral, free radical scavenging, antidiabetic, anti-hepatotoxic, diuretic, antipyretic, anti-oxaluria, anti-tumour, antibacterial, antifungal, anti-inflammatory, antimicrobial, and cardioprotective. This review summarizes traditional uses and offers up to date data for future research on B. pacumbis.

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