Genital abnormalities associated to lack of uterine adenogenesis or endometrial glands dysgenesis of female dromedary camels (Camelus dromedarius)

Abstract

Background: The developmental disruption of Müllerian duct and the endometrial dynamic can generate genital lesions that could contribute to infertility. Aim: This paper discusses two cases of genital conditions associated to endometrial glands pathologies in nulliparous female camels. Methods: Macroscopic exams and histopathologic description were performed on congenital and acquired genital abnormalities with endometrial glands anomalies. Results: The first case is endometrial glands agenesis associated to unilateral uterine aplasia and the second case is endometrial glands dysgenesis associated to metritis. The prevalence of each case is estimated to 0.6%. The most specific microscopic features associated to the endometrial glands agenesis were the presence of endometrial stroma proliferation and homogenous hyalinization of the myometrium. The acute metritis was associated to endometrial activated stroma with focal infiltration with inflammatory cells on the endometrium and the myometrium and spontaneous endometrial glands dysgenesis. Conclusion: This study reveals the importance of congenital abnormalities during routine reproductive examination of peripubertal animals, as well as the association of histopathological complementary examination for the research functional and inflammatory anomalies of the uterus. Genetic screening of breeders would be very important in the search for genetic risk factors associated with these congenital pathologies, which can be disseminated by reproductive biotechnologies.

Keywords

• adenogenesis
• camel
• metritis
• uterine aplasia
• uterine glands